- A high-throughput pipeline for scalable kit-free RNA extraction 6 December, 2021 Posted in: Publication - Ping Han, Maybelle K. Go, Jeng Yeong Chow, Bo Xue, Yan Ping Lim, Michael A. Crone, Marko Storch, Paul S. Freemont & Wen Shan Yew Given the global over-reliance on commercial, kit-based RNA extraction in the molecular diagnoses of infectious diseases such as SARS-CoV-2, past challenges in the event of supply chain disruptions have hindered testing capacity in times of need. Apart from supply
- Building Biofoundry India: challenges and path forward 21 July, 2021 Posted in: Publication - Binay Panda, Pawan K Dhar Abstract Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design-build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we see the facility add a substantial value in
- DNA Scanner: a web application for comparing DNA synthesis feasibility, price and turnaround time across vendors 18 October, 2021 Posted in: Publication - DNA synthesis has become a major enabler of modern bioengineering, allowing scientists to simply order online in silico-designed DNA molecules. Rapidly decreasing DNA synthesis service prices and the concomitant increase of research and development scales bolstered by computer-aided DNA design tools and laboratory automation has driven up the demand for synthetic DNA.
- Building a biofoundry 18 October, 2021 Posted in: Publication - A biofoundry provides automation and analytics infrastructure to support the engineering of biological systems. It allows scientists to perform synthetic biology and aligned experimentation on a high-throughput scale, massively increasing the solution space that can be examined for any given problem or question.
- A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics 19 May, 2021 Posted in: Publication - Michael A. Crone, Miles Priestman, Marta Ciechonska, Kirsten Jensen, David J. Sharp, Arthi Anand, Paul Randell, Marko Storch & Paul S. Freemont A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics | Nature Communications
- GBA Webinar with Dr Rosalind Le Feuvre & Dr Mark Dörr 14 April, 2021 Posted in: Events - 2021 Global Biofoundries Alliance Webinar Series April 20th 2021 @ 1-2 pm CET Register in advance for this webinar: https://lbnl.zoom.us/webinar/register/WN_x6S_QgwHTFeSnBCSmsfxMg A recording of the webinar will be made publicly available after the event for those unable to attend. This is a public webinar, so please do share this announcement with others that may be interested
- London Biofoundry testing and pooling projects 19 March, 2021 Posted in: Research - In early 2020, due to reagent and labware shortages, there were significant limitations on SARS-CoV-2 testing capacity worldwide, with the UK’s diagnostic capacity at only 10 000 tests per day at the beginning of April. The London Biofoundry worked together with NHS colleagues to successfully increase testing capacity in accredited NHS laboratories at the St
- Building a global alliance of biofoundries 18 November, 2019 Posted in: News - Nathan Hillson, Mark Caddick, […]Paul S. Freemont Nature Communications volume 10, Article number: 2040 (2019) Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research. Many biofoundries are being built and a Global Biofoundry Alliance has recently been established to coordinate activities worldwide.
- Global Biofoundry Meeting, London, June 2018 25 June, 2019 Posted in: News - A meeting was held at Imperial College London on June 21st/22nd 2018, which gathered fifteenof the leading synthetic biology biofoundries from around the world to discuss current activities and exchange information on key capabilities and projects being developed by these groups. Originally posted by SynbiCITE on 25 June, 2018 The meeting explored opportunities for collaboration and