RoboMoClo: A Robotics-Assisted Modular Cloning Framework for Multiple Gene Assembly in Biofoundry

Dong Hun Kang, Sung Cheon Ko, Yu Been Heo, Hyun Jeong Lee, Han Min Woo Abstract Efficient and versatile DNA assembly frameworks have had an impact on promoting synthetic biology to build complex biological systems. To accelerate system development, laboratory automation (or biofoundry) provides an opportunity to construct organisms and DNA assemblies via computer-aided design.

A high-throughput pipeline for scalable kit-free RNA extraction

Ping Han, Maybelle K. Go, Jeng Yeong Chow, Bo Xue, Yan Ping Lim, Michael A. Crone, Marko Storch, Paul S. Freemont & Wen Shan Yew Given the global over-reliance on commercial, kit-based RNA extraction in the molecular diagnoses of infectious diseases such as SARS-CoV-2, past challenges in the event of supply chain disruptions have hindered testing capacity in times of need. Apart from supply

DNA Scanner: a web application for comparing DNA synthesis feasibility, price and turnaround time across vendors

DNA synthesis has become a major enabler of modern bioengineering, allowing scientists to simply order online in silico-designed DNA molecules. Rapidly decreasing DNA synthesis service prices and the concomitant increase of research and development scales bolstered by computer-aided DNA design tools and laboratory automation has driven up the demand for synthetic DNA.